4-Bromo-N-methyl-2-nitroaniline(CAS: 53484-26-7)

4-Bromo-N-methyl-2-nitroaniline (CAS: 53484-26-7) is a white crystalline solid with a molecular weight of approximately 251.04 g/mol. It has a pKa of around 5.2 and is slightly soluble in water. This compound is known for its high reactivity, particularly towards nucleophiles. It is often used in organic synthesis and as an intermediate in the production of dyes and pharmaceuticals.

4-Bromo-N-methyl-2-nitroaniline (CAS: 53484-26-7) is typically synthesized via the nitration of 4-chloro-N-methylaniline followed by bromination. The process involves careful control of reaction conditions to achieve high yields and selectivity. Commonly used catalysts include sulfuric acid, and the reaction often requires cooling to maintain reactivity and control byproducts.

4-Bromo-N-methyl-2-nitroaniline (CAS: 53484-26-7) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the production of dyes and pigments, and it plays a role in the development of sensors and semiconductors due to its unique chemical properties.

When handling 4-Bromo-N-methyl-2-nitroaniline (CAS: 53484-26-7), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.