[3-(Methacryloylamino)phenyl]boronic acid(CAS: 48150-45-4)

[3-(Methacryloylamino)phenyl]boronic acid (CAS: 48150-45-4) is a white crystalline solid with a molecular weight of approximately 237.2 g/mol. It is slightly soluble in water and more soluble in organic solvents such as methanol and ethanol. The compound exhibits high reactivity towards nucleophiles due to the presence of the boronic acid moiety, making it useful in various organic reactions. It also shows good stability under neutral and slightly acidic conditions.

[3-(Methacryloylamino)phenyl]boronic acid (CAS: 48150-45-4) is typically synthesized by reacting 3-aminophenol with methacryloyl chloride in the presence of a base like triethylamine. The reaction proceeds via a nucleophilic substitution mechanism, leading to the formation of the desired product. The yield is usually around 70-80% due to the high reactivity of the methacryloyl moiety.

[3-(Methacryloylamino)phenyl]boronic acid (CAS: 48150-45-4) finds applications in the pharmaceutical industry for its role as a ligand in chelation reactions and as a building block in the synthesis of complex molecules. It is also used in the polymer industry as a monomer for the preparation of functionalized polymers. Additionally, it is employed in the development of sensors for detecting boron compounds and in semiconductor industry for its role in surface modification and functionalization.

When handling [3-(Methacryloylamino)phenyl]boronic acid (CAS: 48150-45-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be carefully cleaned up using appropriate solvents, and the area should be flushed with water if necessary. Always refer to the Safety Data Sheet (SDS) for detailed guidance on handling and disposal.