Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine(CAS: 56001-37-7)

Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine (CAS: 56001-37-7) is a phosphonate ester derivative of guanosine. It crystallizes in a stable form with a high melting point. The molecular weight is approximately 942.16 g/mol. It has poor water solubility and exhibits low reactivity under normal conditions. This compound is stable under acidic and basic conditions but susceptible to hydrolysis in the presence of moisture.

Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine (CAS: 56001-37-7) is synthesized using a multi-step process involving the condensation of guanosine with a phosphonate, followed by a series of phosphonate esterification reactions. Commonly used catalysts include titanium(IV) isopropoxide and other organometallic compounds. The reaction yields around 85% of the desired product. The process is carried out in a controlled environment to ensure high purity and yield.

Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine (CAS: 56001-37-7) is primarily used in the pharmaceutical industry for the development of novel nucleoside analogs with potential antiviral and anticancer properties. It is also explored in the field of molecular biology for studying nucleic acid structures and functions. Additionally, it has applications in the sensor industry for detecting specific nucleic acids and in the semiconductor industry for electronic applications.

When handling Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine (CAS: 56001-37-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of spills, they should be immediately cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.