2-Chloro-5-nitrobenzaldehyde(CAS: 6361-21-3)

2-Chloro-5-nitrobenzaldehyde is a yellow to orange crystalline solid with a molecular weight of 211.01 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It is relatively stable but may react with reducing agents. The compound is used in the synthesis of various organic compounds due to its functional groups.

2-Chloro-5-nitrobenzaldehyde is typically synthesized via the nitration of 2-chlorobenzaldehyde followed by the conversion of the nitro group. Common methods involve the use of nitric acid and sulfuric acid as reagents, with careful control of temperature and reaction time to achieve high yield and selectivity.

2-Chloro-5-nitrobenzaldehyde is utilized in pharmaceuticals, where it serves as an intermediate in the production of certain drugs. It is also used in the synthesis of dyes, polymers, and sensors due to its functional groups. Its reactivity makes it valuable in semiconductor manufacturing as well.

When handling 2-Chloro-5-nitrobenzaldehyde, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up with care using appropriate absorbents, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.