Methyl 4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate(CAS: 1455091-10-7)

Methyl 4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate (CAS: 1455091-10-7) is a crystalline compound with a molecular weight of approximately 316.31 g/mol. It has a solubility of 0.1 g/L in water and is slightly soluble in common organic solvents like acetone and ethanol. This compound is relatively stable but can react with bases to form alkali salts. It is generally insoluble in water but has good solubility in organic solvents.

Methyl 4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate (CAS: 1455091-10-7) is typically synthesized through a multi-step reaction sequence involving the condensation of a phenoxy derivative with an isoquinoline carboxylic acid. This process often uses a Lewis acid catalyst, such as aluminum chloride, to facilitate the nucleophilic substitution reaction. The final product is obtained with good selectivity and yield, typically around 80%. This compound is often prepared in a laboratory setting for further chemical modification or analysis.

Methyl 4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate (CAS: 1455091-10-7) is primarily used in the pharmaceutical industry for the development of novel drug candidates due to its unique chemical structure. It is also utilized in the research and development of new materials for sensors and semiconductors, where its specific properties may offer advantages in sensitive detection and electronic applications.

When handling Methyl 4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate (CAS: 1455091-10-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to prevent skin contact and eye irritation. It is advisable to use a fume hood when performing operations to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. It is recommended to consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.