Diethyl 2,6-pyridinedicarboxylate(CAS: 15658-60-3)

Diethyl 2,6-pyridinedicarboxylate (CAS: 15658-60-3) is a crystalline solid with a molecular weight of approximately 250.27 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. Chemically, it is relatively stable but can undergo ester hydrolysis under acidic or basic conditions. It has a high melting point around 230°C and is a colorless to pale yellow crystalline compound.

Diethyl 2,6-pyridinedicarboxylate (CAS: 15658-60-3) is commonly synthesized by the condensation of 2,6-pyridinedicarboxylic acid with diethylamine. The reaction typically proceeds under mild conditions with a yield of around 80-85%. Catalysts such as potassium carbonate are often used to facilitate the reaction and improve selectivity. The synthesis is carried out in organic solvents like methanol or ethanol.

Diethyl 2,6-pyridinedicarboxylate (CAS: 15658-60-3) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the polymer industry, where it acts as a plasticizer or stabilizer. Additionally, it is used in the production of sensors and semiconductors due to its chemical stability and specific functional groups.

When handling Diethyl 2,6-pyridinedicarboxylate (CAS: 15658-60-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight and heat sources. Fume hoods should be used during handling to minimize inhalation. In case of a spill, it should be cleaned up immediately with appropriate absorbent material and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.