5-Bromo-2-methoxyisonicotinic acid(CAS: 886365-22-6)

5-Bromo-2-methoxyisonicotinic acid is a white crystalline solid with a molecular weight of approximately 222.03 g/mol. It has a solubility of about 10.1 mg/mL in water and is less soluble in organic solvents. This compound is moderately reactive, especially under basic conditions, and can undergo nucleophilic substitution reactions.

5-Bromo-2-methoxyisonicotinic acid is typically synthesized through a bromination reaction of 2-methoxyisonicotinic acid using bromine in the presence of an appropriate solvent and catalyst. The yield is usually around 85-90%, and the selectivity for bromination is high.

5-Bromo-2-methoxyisonicotinic acid is used in the pharmaceutical industry for the synthesis of certain drug candidates. It also finds applications in the polymer industry for the modification of polymers and in chemical sensors for detecting specific analytes.

When handling 5-Bromo-2-methoxyisonicotinic acid, it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate methods, and the material safety data sheet (MSDS) should be consulted for specific disposal procedures.