Apixaban Impurity 19(CAS: 503615-07-4)

Apixaban Impurity 19 (CAS: 503615-07-4) is a crystalline compound with a molecular weight of approximately 322.23 g/mol. It is sparingly soluble in water and ethanol. The impurity shows limited reactivity under normal conditions, making it stable in various environments. It is typically characterized by its melting point range and solubility in organic solvents.

Apixaban Impurity 19 (CAS: 503615-07-4) is synthesized through a series of reaction steps involving organic transformations, including coupling reactions and acetylation. The synthesis typically requires the use of azeotropic drying and recrystallization techniques to purify the product. Yield and selectivity are crucial in this process, and common reagents include dichloromethane, acetic anhydride, and triethylamine.

Apixaban Impurity 19 (CAS: 503615-07-4) is primarily used in the pharmaceutical industry, specifically in the development and quality control of apixaban, an anticoagulant drug. It is also relevant in the chemical research and development sector for studying impurity profiles and drug metabolism.

When handling Apixaban Impurity 19 (CAS: 503615-07-4), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be carried out in a well-ventilated fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and follow the safety data sheet (SDS) guidelines for proper disposal. Always consult the SDS for detailed safety information.