Compound Q&A

How is Apixaban Impurity 19 (CAS: 503615-07-4) typically synthesized?

Answer

Apixaban Impurity 19
Apixaban Impurity 19 (CAS: 503615-07-4) is synthesized through a series of reaction steps involving organic transformations, including coupling reactions and acetylation. The synthesis typically requires the use of azeotropic drying and recrystallization techniques to purify the product. Yield and selectivity are crucial in this process, and common reagents include dichloromethane, acetic anhydride, and triethylamine.

About

English Name Apixaban Impurity 19
Molecular Formula C22H22N4O4
Molecular Weight 406.4420000000001 g/mol
SMILES O=C(C1=NN(C2=CC=C(OC)C=C2)C3=C1CCN(C4=CC=C(N)C=C4)C3=O)OCC
InChIKey UVAQGQOGOJLALA-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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