2-Hydroxyethanesulfonic acid - 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one (1:1)(CAS: 827022-33-3)

2-Hydroxyethanesulfonic acid - 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one is a crystalline compound with a molecular weight of approximately 522.7 g/mol. It has a solubility of around 1.3 g/L in water. The compound exhibits moderate reactivity, particularly towards nucleophiles, and is stable under neutral to mildly acidic conditions. It is not flammable and has a low risk of reactivity with common laboratory reagents.

2-Hydroxyethanesulfonic acid - 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one is typically synthesized via a multi-step process involving the formation of an acetyl derivative, cyclization, and subsequent modification with piperazine and pyridine groups. Commonly used reagents include acetic anhydride, piperazine, and 2-methyl-5-(2-pyridyl)-1H-pyrimidine-4,6(1H,5H)-dione, with high selectivity and good yields achievable under optimized reaction conditions.

2-Hydroxyethanesulfonic acid - 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one is primarily used in the pharmaceutical industry for the development of novel antiviral and anticancer drugs. It also finds applications in the polymer industry for the synthesis of advanced polymers with specific properties, and in the semiconductor industry as a component in certain etching solutions.

When handling 2-Hydroxyethanesulfonic acid - 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, it is recommended to wear protective gloves, goggles, and a lab coat to prevent skin and eye contact. Work must be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up with appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.