3-(2-Bromophenyl)acrylic acid(CAS: 7499-56-1)

3-(2-Bromophenyl)acrylic acid (CAS: 7499-56-1) is a crystalline solid with a molecular weight of approximately 245.01 g/mol. It has a low solubility in water (0.1 g/100 mL at 20°C) and is soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is stable under normal conditions but should be stored in a cool, dry place, away from direct sunlight.

3-(2-Bromophenyl)acrylic acid is typically synthesized through a bromination reaction of 2-hydroxybenzaldehyde followed by dehydration and subsequent acidification. Commonly, N-bromosuccinimide (NBS) in the presence of an initiator like azobisisobutyronitrile (AIBN) is used as the brominating agent. The reaction yields a brominated product with high selectivity and good yield, making it a practical method for industrial production.

3-(2-Bromophenyl)acrylic acid (CAS: 7499-56-1) is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the polymer industry for the production of functional coatings and adhesives. It is also employed in the development of sensors and semiconductors due to its unique chemical properties.

When handling 3-(2-Bromophenyl)acrylic acid (CAS: 7499-56-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. This compound should be used in a fume hood to minimize inhalation risks. In case of a spill, neutralize the acid with a base and carefully clean up the area. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.