Methyl 4-[(1S)-1-aminoethyl]benzoate(CAS: 222714-37-6)

Methyl 4-[(1S)-1-aminoethyl]benzoate (CAS: 222714-37-6) is a white crystalline solid with a molecular weight of approximately 222.25 g/mol. It has a pKa of around 9.4 and a solubility of about 1.5 g/L in water. This compound is moderately reactive towards bases and has good solubility in common organic solvents. It is stable under normal conditions but should be stored away from strong oxidizing agents and light.

Methyl 4-[(1S)-1-aminoethyl]benzoate (CAS: 222714-37-6) is synthesized through the condensation of benzoic acid and (1S)-1-aminopropan-2-ol using a dehydrating agent like anhydrous sodium carbonate. The reaction is carried out under mild conditions and typically yields 85-90% of the desired product. Aqueous work-up and recrystallization from ethanol provide the final product in a crystalline form.

Methyl 4-[(1S)-1-aminoethyl]benzoate (CAS: 222714-37-6) is used in the pharmaceutical industry for the synthesis of various biologically active compounds. It also finds applications in the polymer industry as a monomer and in the development of sensor devices. Additionally, it is utilized in the semiconductor industry due to its specific functional groups that can be exploited for various surface modifications.

When handling Methyl 4-[(1S)-1-aminoethyl]benzoate (CAS: 222714-37-6), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a fume hood and away from strong oxidizing agents and heat sources. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.