2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1)(CAS: 25646-77-9)

2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1) is a crystalline solid with a molecular weight of approximately 357.43 g/mol. It has a pKa around 10.3, indicating basicity. The compound is moderately soluble in water but less so in organic solvents. It exhibits good reactivity towards proton donors and nucleophiles due to the presence of the amine and hydroxyl groups.

2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1) can be synthesized by reacting 2-aminoethanol with 4-amino-3-methylphenylethylamine hydrochloride in the presence of sulfuric acid and sodium sulfate as a catalyst. The reaction yields a 1:1 sulfate salt with high selectivity and good yield under mild conditions.

2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1) finds applications in pharmaceuticals due to its chemical structure and reactivity, as well as in the production of polymers for their functional properties. It is also used in the development of new sensor materials and as a precursor in semiconductor manufacturing processes.

When handling 2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1), ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated area or under a fume hood to avoid inhalation of aerosols. Follow standard laboratory safety procedures and keep the material away from strong acids and oxidizers. Store at room temperature in a dry, well-ventilated area. In case of spill, use appropriate spill cleanup procedures and refer to the Material Safety Data Sheet (MSDS) for detailed instructions.