Compound Q&A

How is 2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1) (CAS: 25646-77-9) typically synthesized?

Answer

2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1)
2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1) can be synthesized by reacting 2-aminoethanol with 4-amino-3-methylphenylethylamine hydrochloride in the presence of sulfuric acid and sodium sulfate as a catalyst. The reaction yields a 1:1 sulfate salt with high selectivity and good yield under mild conditions.

About

CAS No 25646-77-9
English Name 2-[(4-Amino-3-methylphenyl)(ethyl)amino]ethanol sulfate (1:1)
Molecular Formula C11H20N2O5S
Molecular Weight 292.36 g/mol
SMILES CCN(CCO)C1=CC(=C(C=C1)N)C.OS(=O)(=O)O
InChIKey GVEYRUKUJCHJSR-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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