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Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate(CAS: 28416-84-4)
CAS Number
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Other Suppliers for Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate
Basic Information
Molecular Formula
C22H28F2O5
Molecular Weight
410.46 g/mol
Physical Properties
Boiling Point
508.894 °C at 760 mmHg
Flash Point
261.57 °C
Chemical Identifiers
SMILES
COC(=O)[C@]2(O)[C@@]3(C)C[C@H](O)[C@]4(F)[C@@]\1(C)/C=C\C(=O)/C=C/1[C@@H](F)C[C@H]4[C@@H]3C[C@H]2C
InChIKey
HTJSTTZFHWMHDB-GQKYHHCASA-N
Database References
FAQ
Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate (CAS: 28416-84-4) is a crystalline solid with a molecular weight of approximately 424.39 g/mol. It is sparingly soluble in water and methanol. Chemically, it is reactive towards nucleophiles and can undergo esterification and hydrolysis reactions. The compound is stable under normal storage conditions but requires handling in a fume hood to avoid inhalation exposure.
Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate (CAS: 28416-84-4) is typically synthesized via a multistep process involving the synthesis of the corresponding 17-carboxyandrostene, followed by the introduction of the fluoro substituents and the hydroxylation at C-11 and C-17 positions. The reaction often requires the use of specialized catalysts and reagents, with high chemical selectivity, and yields of around 75% can be achieved.
Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate (CAS: 28416-84-4) is primarily used in the pharmaceutical industry for the development of hormonal drugs. The compound may also be used in the research and development of new therapeutic agents. It is less commonly used in other industries such as polymers, sensors, and semiconductors.
When handling Methyl (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylate (CAS: 28416-84-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, the area should be evacuated, and the spill should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Cai Guodong
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