(6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid | CAS No. 397864-63-0

(6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

Basic Information

CAS Number

397864-63-0

Molecular Formula

C26H28F2O7

Molecular Weight

490.5 g/mol

AD

Basic Physical Properties

Melting Point

>198°C (dec.)

Boiling Point

638.4±55.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Flash Point

339.9±31.5 °C

Solubility

DMSO (Slightly)

Vapor Pressure

0.0±2.0 mmHg at 25°C

C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)O)OC(=O)c5ccco5)C)O)F)C)F

InChI

InChI=1S/C26H28F2O7/c1-13-9-15-16-11-18(27)17-10-14(29)6-7-23(17,2)25(16,28)20(30)12-24(15,3)26(13,22(32)33)35-21(31)19-5-4-8-34-19/h4-8,10,13,15-16,18,20,30H,9,11-12H2,1-3H3,(H,32,33)/t13-,15+,16+,18+,20+,23+,24+,25+,26+/m1/s1

InChIKey

QOANMINPJDURAZ-VEGHOPOESA-N

LogP

3.824600000000003

Topological Polar Surface Area

114.04000000000002 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

1040

Synonyms & References

English

  • 1W3NSQ8V5D
  • M10 OF fluticasone furoate
  • GW 694301X
  • Q27252974
  • (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-((furan-2-carbonyl)oxy)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid

FAQ

What is (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid (CAS: 397864-63-0)?

This compound is a derivative of androstenedione, characterized by its unique substituents including fluorine atoms and a furoyl group. It is a white to off-white solid with a specific melting point and is used in research and pharmaceutical applications due to its structural and functional properties.

What are the main uses of (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid (CAS: 397864-63-0)?

This compound is primarily used in scientific research, particularly in the development of new drugs and hormone-related studies. It may also be used in pharmaceutical applications as a precursor or intermediate in the synthesis of other compounds.

Is (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid (CAS: 397864-63-0) safe?

The safety of this compound depends on the context and application. It is generally safe when used under controlled laboratory conditions with appropriate protective measures, such as gloves and goggles. However, it should be handled with care due to its potential for skin and eye irritation.

How should (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(2-furoyloxy)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid (CAS: 397864-63-0) be stored?

Store this compound in a cool, dry place away from direct sunlight and heat sources. Keep the container tightly closed to prevent moisture absorption. Store it at room temperature (15-25°C) and avoid exposure to temperatures above 30°C. Use a properly sealed, airtight container to maintain its stability and purity.

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