1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline(CAS: 101555-62-8)

1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline (CAS: 101555-62-8) is a crystalline compound with a molecular weight of approximately 453.36 g/mol. It has a high solubility in organic solvents such as dimethyl sulfoxide (DMSO) and chloroform. The compound is known for its stability and moderate reactivity in various chemical reactions, particularly in peptide synthesis and medicinal chemistry.

1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline (CAS: 101555-62-8) can be synthesized via the condensation of fluoren-9-ylmethanol with D-proline in the presence of a coupling agent such as 1-hydroxybenzotriazole (HOBt) and a base like 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). The reaction yields a high purity product with excellent selectivity and yield, making it a key intermediate in various peptide synthesis applications.

1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline (CAS: 101555-62-8) is extensively used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of bioactive peptides and proteins, as well as in the development of polymeric materials with enhanced biological and mechanical properties. Its ability to form stable amide bonds makes it valuable in both fields.

When handling 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline (CAS: 101555-62-8), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials and disposed of according to local hazardous waste regulations. For detailed safety information, refer to the material safety data sheet (MSDS) or safety data sheet (SDS).