Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (1:1)(CAS: 40126-30-5)

Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5) is a white crystalline powder with a molecular weight of approximately 246.2 g/mol. It has good solubility in water and alcohol. This compound is less reactive under normal conditions but shows moderate acidity due to the presence of the hydrochloride group. It is stable in dry conditions but should be stored in a sealed container to prevent hydrolysis and degradation.

Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5) can be synthesized through the condensation of (S)-4-hydroxy-L-proline with methylamine followed by protonation with hydrochloric acid. Commonly, this process involves the use of a mild acid catalyst and debenzylation steps to achieve the desired product with high selectivity and yield.

Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymer properties, and in the sensor industry for developing biosensors. Additionally, it has applications in the semiconductor industry for surface modification and as a reagent in chemical synthesis.

When handling Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry, and well-ventilated area. It should be used in a fume hood to minimize exposure. In case of spills, they should be cleaned up promptly with absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.