Compound Q&A

How is Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5) typically synthesized?

Answer

Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (1:1)
Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (CAS: 40126-30-5) can be synthesized through the condensation of (S)-4-hydroxy-L-proline with methylamine followed by protonation with hydrochloric acid. Commonly, this process involves the use of a mild acid catalyst and debenzylation steps to achieve the desired product with high selectivity and yield.

About

CAS No 40126-30-5
English Name Methyl (4S)-4-hydroxy-L-prolinate hydrochloride (1:1)
Molecular Formula C6H12ClNO3
Molecular Weight 181.62 g/mol
SMILES COC(=O)C1CC(CN1)O.Cl
InChIKey KLGSHNXEUZOKHH-FHAQVOQBSA-N
Last Updated: 2025-09-10 15:15

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