4-KETO 13-CIS-RETINOIC ACID METHYL ESTER(CAS: 71748-57-7)

4-KETO 13-CIS-RETINOIC ACID METHYL ESTER is a crystalline compound with a molecular weight of approximately 322.38 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and dimethyl sulfoxide. This compound is relatively stable but can react with bases to form retinoic acid. It is commonly used in pharmaceutical research and has a melting point of around 65-68°C.

4-KETO 13-CIS-RETINOIC ACID METHYL ESTER is typically synthesized through a series of steps involving the modification of retinol. The reaction involves the oxidation of retinol to retinal, followed by the isomerization of 13-cis-retinal to 13-cis-retinol, and finally the formation of the methyl ester through esterification. This process often utilizes chemical reagents such as iodine and sulfuric acid, and requires careful control of reaction conditions to achieve high yields and selectivity.

4-KETO 13-CIS-RETINOIC ACID METHYL ESTER is widely used in the pharmaceutical industry for its potential therapeutic applications. It is also utilized in the development of retinoid-based drugs and in cosmetics for its skin care properties. Additionally, this compound is of interest in the research of sensors and semiconductors due to its unique optical and electrical properties.

When handling 4-KETO 13-CIS-RETINOIC ACID METHYL ESTER, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight to prevent degradation. In case of a spill, ensure the area is well-ventilated and use appropriate absorbent materials. It is crucial to consult the Safety Data Sheet (SDS) for specific handling and disposal instructions to ensure safety.