Quinoline-4-carbothioamide(CAS: 74585-98-1)

Quinoline-4-carbothioamide is a solid with a crystalline form and a molecular weight of approximately 228.24 g/mol. It is slightly soluble in water but more soluble in organic solvents like DMSO. Chemically, it is relatively stable but can react with strong acids or bases. Its reactivity is moderate and it is not prone to spontaneous decomposition under normal storage conditions.

Quinoline-4-carbothioamide is typically synthesized via a multistep process that includes the preparation of a thioamide, followed by its reaction with 4-chloroquinoline. Commonly used catalysts include sodium hydride, and the overall yield is moderate, around 50-70%.

Quinoline-4-carbothioamide is used in the pharmaceutical industry for its potential as an antifungal agent. It is also explored in the polymer industry for its catalytic properties and in sensor technology for its reactivity with certain analytes.

When handling Quinoline-4-carbothioamide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood. In case of a spill, use appropriate spill kits and follow local safety guidelines. Always refer to the Safety Data Sheet (SDS) for detailed safety information.