Compound Q&A

How is Quinoline-4-carbothioamide (CAS: 74585-98-1) typically synthesized?

Answer

Quinoline-4-carbothioamide
Quinoline-4-carbothioamide is typically synthesized via a multistep process that includes the preparation of a thioamide, followed by its reaction with 4-chloroquinoline. Commonly used catalysts include sodium hydride, and the overall yield is moderate, around 50-70%.

About

CAS No 74585-98-1
English Name Quinoline-4-carbothioamide
Molecular Formula C10H8N2S
Molecular Weight 188.26 g/mol
SMILES C1=CC=C2C(=C1)C(=CC=N2)C(=S)N
InChIKey CVBYCKKBOIJRTK-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59

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