2-(2-Thienyl)phenol(CAS: 106584-13-8)

2-(2-Thienyl)phenol (CAS: 106584-13-8) is a crystalline solid with a molecular weight of approximately 182.18 g/mol. It has a low melting point of about 73-74°C. The compound is slightly soluble in water but soluble in common organic solvents such as ethanol and acetone. It is chemically stable but can react with strong oxidizing agents and light exposure. This compound is often used in organic synthesis due to its reactivity.

2-(2-Thienyl)phenol is typically synthesized via the phenol-thiophene coupling reaction. A common method involves the reaction of 2-chloro-2-thiophenethiol with phenol in the presence of a base like sodium hydroxide. The reaction is carried out in an aprotic polar solvent, yielding a product with excellent selectivity and moderate yield. This method is widely used in academic and industrial settings.

2-(2-Thienyl)phenol (CAS: 106584-13-8) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of medicinal compounds and is also utilized in the production of functional polymers. Additionally, due to its chemical properties, it finds applications in sensor technology and semiconductor manufacturing.

When handling 2-(2-Thienyl)phenol (CAS: 106584-13-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, use appropriate containment and clean up with care, as the compound can react with oxidizing agents. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.