Compound Q&A

How is Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9) typically synthesized?

Answer

Ethyl 5-(chloromethyl)-2-furoate
Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9) can be synthesized via the reaction of ethyl furan-2-carboxylate with phosgene in the presence of a catalyst such as N,N-dimethylformamide (DMF). The reaction produces the title compound with good yield and selectivity. This method is commonly used in academic and industrial settings.

About

CAS No 2528-00-9
English Name Ethyl 5-(chloromethyl)-2-furoate
Molecular Formula C8H9ClO3
Molecular Weight 188.61 g/mol
SMILES CCOC(=O)C1=CC=C(O1)CCl
InChIKey JBACYJRMCXLIQU-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31

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