3-(2,4-Dihydroxyphenyl)acrylic acid(CAS: 614-86-8)

3-(2,4-Dihydroxyphenyl)acrylic acid (CAS: 614-86-8) is a white to off-white crystalline solid with a molecular weight of approximately 190.15 g/mol. It is slightly soluble in water and readily soluble in organic solvents like ethanol and acetone. The compound is reactive, especially towards nucleophiles and reducing agents, making it useful in various synthetic applications.

3-(2,4-Dihydroxyphenyl)acrylic acid is typically synthesized via the condensation of 2,4-dihydroxybenzaldehyde with acryloyl chloride. The reaction proceeds under mild conditions, often using a catalytic amount of a Lewis acid like zinc chloride to improve yield and selectivity. The final product is isolated by crystallization and recrystallization to obtain the desired purity.

3-(2,4-Dihydroxyphenyl)acrylic acid (CAS: 614-86-8) finds applications in various industries, including pharmaceuticals, where it serves as a key intermediate for the synthesis of certain drugs. It is also used in the production of polymers, specifically in the development of biodegradable materials and in the manufacturing of photolithographic resists for semiconductor fabrication.

When handling 3-(2,4-Dihydroxyphenyl)acrylic acid (CAS: 614-86-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution using absorbent materials and the appropriate safety measures. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.