2-(4-Nitrophenyl)ethanol(CAS: 100-27-6)

2-(4-Nitrophenyl)ethanol (CAS: 100-27-6) is a colorless to light yellow liquid with a molecular weight of approximately 198.14 g/mol. It has a density of about 1.08 g/cm³ and a boiling point of around 188°C. This compound is moderately soluble in water and readily soluble in organic solvents like ethanol and acetone. It is not highly reactive under normal conditions but can undergo nitro reduction.

2-(4-Nitrophenyl)ethanol (CAS: 100-27-6) is synthesized by the nitration of 2-phenylethanol followed by reduction of the nitro group to an amino group and then to an alcohol. Common reagents used include nitric acid in the presence of sulfuric acid. The process involves careful control of temperature and concentration to achieve high yield and selectivity.

2-(4-Nitrophenyl)ethanol (CAS: 100-27-6) is primarily used in the pharmaceutical industry as an intermediate in drug synthesis. It is also utilized in the production of various dyes and pigments, and can be found in some polymer formulations and as a component in certain sensors and semiconductors.

When handling 2-(4-Nitrophenyl)ethanol (CAS: 100-27-6), ensure appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation. Store in a cool, dry place away from direct sunlight and heat sources. In case of spill, immediately clean up using appropriate materials and consult the Safety Data Sheet (SDS) for detailed emergency procedures.