4-(3-Oxobutyl)phenyl acetate(CAS: 3572-06-3)

4-(3-Oxobutyl)phenyl acetate is a colorless liquid with a molecular weight of approximately 212.26 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly towards nucleophilic substitution reactions. Its vapor pressure is low, and it exhibits typical ester properties with respect to reactivity and acidity.

4-(3-Oxobutyl)phenyl acetate is typically synthesized via the esterification of 4-(3-oxobutyl)phenol with acetic acid. Commonly, a catalytic amount of a strong acid such as sulfuric acid is used. The reaction is carried out under mild conditions, and the product is isolated by washing, drying, and distillation. The yield is generally around 80-85%, with good selectivity towards the desired ester product.

4-(3-Oxobutyl)phenyl acetate is used in the pharmaceutical industry for the preparation of certain drug intermediates due to its chemical functional groups. It is also utilized in the polymer industry for modifying the properties of synthetic polymers. Additionally, it finds applications in the sensor technology sector for chemical sensing applications. Its use in semiconductors is limited but can be explored for specific material properties.

Proper personal protective equipment (PPE) is essential when handling 4-(3-Oxobutyl)phenyl acetate, including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.