2-Chloro-3-methylpyridine 1-oxide(CAS: 91668-83-6)

2-Chloro-3-methylpyridine 1-oxide (CAS: 91668-83-6) is a crystalline solid with a molecular weight of approximately 182.6 g/mol. It has a melting point of around 125-127°C and is sparingly soluble in water but more soluble in organic solvents like ethanol and dichloromethane. This compound is moderately reactive with nucleophiles and can undergo substitution reactions.

2-Chloro-3-methylpyridine 1-oxide (CAS: 91668-83-6) is typically synthesized through the chlorination of 3-methylpyridine followed by oxidation. Commonly, this involves the use of chlorine gas in the presence of a suitable catalyst, such as iron chloride, and subsequent oxidation often employs peroxy compounds or air oxidation. The reaction yield is generally good, and the product can be isolated through recrystallization.

2-Chloro-3-methylpyridine 1-oxide (CAS: 91668-83-6) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It also finds applications in the production of organic semiconductors and as a chemical intermediate in the development of sensors and polymers.

When handling 2-Chloro-3-methylpyridine 1-oxide (CAS: 91668-83-6), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure to work in a well-ventilated area or a fume hood. Spills should be cleaned up with absorbent material and disposed of according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.