3-Fluoro-2-iodotoluene(CAS: 883502-14-5)

3-Fluoro-2-iodotoluene (CAS: 883502-14-5) is a colorless liquid with a molecular weight of approximately 268.07 g/mol. It has a high boiling point of around 235°C and low water solubility. This compound is less reactive than its parent toluene but exhibits potential reactivity in halogenation and substitution reactions.

3-Fluoro-2-iodotoluene is usually synthesized via the reaction of 2-iodotoluene with hydrogen fluoride. The reaction involves a fluoride substitution at the 3-position of the toluene ring, typically conducted in the presence of a Lewis acid catalyst to enhance the reaction selectivity and yield.

3-Fluoro-2-iodotoluene (CAS: 883502-14-5) is primarily used in the pharmaceutical industry for the synthesis of drugs and intermediates. It also finds applications in organic chemistry and materials science, particularly in the production of polymers and sensors.

When handling 3-Fluoro-2-iodotoluene (CAS: 883502-14-5), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its potential to volatilize. Spills should be cleaned up using appropriate methods and materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.