Compound Q&A
What is Avapritinib (CAS: 1703793-34-3)?
Answer
Avapritinib is a selective inhibitor of the PDGFRA D842V mutation, used in the treatment of gastrointestinal stromal tumor (GIST) with the PDGFRA D842V mutation and systemic mastocytosis (SM) with one or more mutations in the KIT gene.
About
CAS No
1703793-34-3
English Name
Avapritinib
Molecular Formula
C26H27FN10
Molecular Weight
498.57 g/mol
SMILES
Cn1cc(cn1)c2cc3c(ncnn3c2)N4CCN(CC4)c5ncc(cn5)[C@@](C)(N)c6ccc(F)cc6
InChIKey
DWYRIWUZIJHQKQ-SANMLTNESA-N
Last Updated: 2025-10-27 20:22
