3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one(CAS: 27402-68-2)

3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2) is a crystalline compound with a molecular weight of approximately 354.12 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound is known for its acidity and reactivity towards nucleophiles. It is stable under neutral to slightly acidic conditions, but may decompose at elevated temperatures or in basic solutions.

3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2) is synthesized through a multi-step process involving the condensation of benzofuran and xanthenone derivatives. The reaction typically requires a Lewis acid catalyst, such as aluminum chloride, and proceeds with good selectivity. The overall yield is moderate to good, and the product is purified using column chromatography.

3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2) is primarily used in the pharmaceutical industry for its potential as an anticancer and antiviral agent. It also finds applications in the development of sensors and semiconductors due to its unique optical and electronic properties.

When handling 3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood, and proper spill cleanup procedures should be followed. The material safety data sheet (MSDS) should be consulted for detailed information on safe handling and storage. Avoid contact with skin and eyes, and dispose of waste according to local regulations.