Compound Q&A

How is 3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2) typically synthesized?

Answer

3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (CAS: 27402-68-2) is synthesized through a multi-step process involving the condensation of benzofuran and xanthenone derivatives. The reaction typically requires a Lewis acid catalyst, such as aluminum chloride, and proceeds with good selectivity. The overall yield is moderate to good, and the product is purified using column chromatography.

About

CAS No 27402-68-2
English Name 3',6'-Dihydroxy-6-nitro-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
Molecular Formula C20H11NO7
Molecular Weight 377.3 g/mol
SMILES C1=CC2=C(C=C1[N+](=O)[O-])C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
InChIKey GYWGQAIDMYGOLU-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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