2-Methyl-2-propanyl (2S)-2-carbamoyl-1-pyrrolidinecarboxylate(CAS: 35150-07-3)

2-Methyl-2-propanyl (2S)-2-carbamoyl-1-pyrrolidinecarboxylate (CAS: 35150-07-3) is a crystalline compound with a molecular weight of 281.35 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. Chemically, it is reactive and can undergo hydrolysis under basic conditions. It has a pKa of approximately 8.0, indicating its basic nature.

2-Methyl-2-propanyl (2S)-2-carbamoyl-1-pyrrolidinecarboxylate (CAS: 35150-07-3) is typically synthesized via a multistep process involving the formation of an intermediate pyrrolidine derivative followed by carbamoylation. This process often involves the use of EDC (N,N'-carbonyldiimidazole) as a coupling agent and a base such as triethylamine. The overall yield is moderate to good, and the reaction is carried out under mild conditions to maintain the stereochemistry at the chiral center.

2-Methyl-2-propanyl (2S)-2-carbamoyl-1-pyrrolidinecarboxylate (CAS: 35150-07-3) is used in the pharmaceutical industry as an intermediate in the synthesis of certain medicinal compounds. It is also utilized in the chemical industry for its reactivity, particularly in the development of new materials and as a building block for complex organic molecules.

When handling 2-Methyl-2-propanyl (2S)-2-carbamoyl-1-pyrrolidinecarboxylate (CAS: 35150-07-3), it is important to use appropriate personal protective equipment (PPE) including gloves and safety goggles. The compound should be stored in a fume hood to minimize inhalation exposure. In case of spill, it should be carefully cleaned up with appropriate absorbent materials. It is crucial to refer to the Material Safety Data Sheet (MSDS) for detailed information and emergency procedures.