Synthesis of novel chromeno[1,6]naphthyridine derivatives in PEG-400 via catalyst-free, one-pot, and multicomponent reactions

Literature Information

Publication Date 2023-11-15
DOI 10.1039/D3NJ03273F
Impact Factor 3.591
Authors

Fatemeh Asilpour, Dariush Saberi, Alireza Hasaninejad


View Original

Abstract

An efficient, one-pot, and catalyst-free pathway was reported for the synthesis of novel chromeno[1,6]naphthyridine derivatives via a multicomponent condensation reaction of salicylaldehyde derivatives, malononitrile dimer, and active methylene compounds. All the reactions were performed in polyethylene glycol-400 as a green solvent at 80 °C. The reactions proceeded with a high-atom economy, and new products were synthesized with good yields and a simple work-up procedure, with water as the only by-product.

Related Literature

A controlled blue-shift in meso-nitrogen aryl fused DIPY and BODIPY skeletons

Marco Farinone, Joanna Cybińska, Miłosz Pawlicki

2019-04-25 Research Article

DOI: 10.1039/C9QO00294D

Clavipines A–C, antiproliferative meroterpenoids with a fused azepine skeleton from the basidiomycete Clitocybe clavipes

Zhaocui Sun, Nailiang Zhu, Man Zhou, Xiaowei Huo, Haifeng Wu, Yu Tian, Junshan Yang, Guoxu Ma, Yan-Long Yang, Xudong Xu

2019-09-30 Research Article

DOI: 10.1039/C9QO01005J

General approach to 2-fluoroalkyl 1,3-azoles via the tandem ring opening and defluorinative annulation of N-fluoroalkyl-1,2,3-triazoles

Vojtěch Košťál, Dominik Täffner, Petr Beier

2019-10-09 Research Article

DOI: 10.1039/C9QO01104H

Inside front cover

Cover

DOI: 10.1039/C9QO90074H

Contents list

Front/Back Matter

DOI: 10.1039/C9QO90094B

Back cover

Cover

DOI: 10.1039/C9QO90095K

Celamonols A–D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus

Yi-Ming Li, Wei-Liang Zhu, Wei-Min Zhao

2019-10-10 Research Article

DOI: 10.1039/C9QO00974D

The inverted solvatochromism of protonated ferrocenylethenyl-pyrimidines: the first example of the solvatochromic reversal of a hybrid organic/inorganic dye

Matías Vidal, Marcos Caroli Rezende, Moisés Domínguez

2019-09-30 Research Article

DOI: 10.1039/C9QO01043B

Platinum(ii)-catalyzed dehydrative C3-benzylation of electron-deficient indoles with benzyl alcohols

Hidemasa Hikawa, Yuuki Matsuura, Shoko Kikkawa, Isao Azumaya

2019-07-17 Research Article

DOI: 10.1039/C9QO00831D

You might also like

Compound Q&A

Is 6-(3-Fluorophenyl)picolinic acid (CAS: 887982-40-3) safe?

6-(3-Fluorophenyl)picolinic acid is generally considered safe for laboratory use...

887982-40-36-(3-Fluorophenyl)pi...
Compound Q&A

What industries use (3R)-3-Pyrrolidinol (CAS: 2799-21-5)?

(3R)-3-Pyrrolidinol is used in the pharmaceutical industry as a precursor for dr...

2799-21-5(3R)-3-Pyrrolidinol
Compound Q&A

What precautions should be taken when handling (4R,5R)-4,5-Diethoxycarbonyl-2,2-dimethyldioxolane (CAS: 59779-75-8)?

When handling (4R,5R)-4,5-Diethoxycarbonyl-2,2-dimethyldioxolane (CAS: 59779-75-...

59779-75-8(4R,5R)-4,5-Diethoxy...
Compound Q&A

How is 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7) typically synthesized?

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is often synthesized via a mult...

90734-71-71-(6-Chloroimidazo[1...
Compound Q&A

What is the market or research trend for N-Ethyl-3,4-dimethylbenzylamine (CAS: 39180-83-1)?

The market for N-Ethyl-3,4-dimethylbenzylamine (CAS: 39180-83-1) remains steady,...

39180-83-1N-Ethyl-3,4-dimethyl...
Compound Q&A

What is Tert-butyl 3-(pyrrolidin-1-yl)azetidine-1-carboxylate (CAS: 1019008-21-9)?

Tert-butyl 3-(pyrrolidin-1-yl)azetidine-1-carboxylate is a chemical compound wit...

1019008-21-9Tert-butyl 3-(pyrrol...
Compound Q&A

What regulatory guidelines apply to 1-Bromo-3-chloro-2,4-dimethoxybenzene (CAS: 1228956-93-1)?

1-Bromo-3-chloro-2,4-dimethoxybenzene (CAS: 1228956-93-1) falls under the classi...

1228956-93-11-Bromo-3-chloro-2,4...
Compound Q&A

Is 8-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS: 1368622-07-4) safe?

The safety of 8-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS: 1368622-07...

1368622-07-48-Bromo-2-methyl-3,4...
Compound Q&A

Is Benzyl [(3S)-2,6-dioxo-3-piperidinyl]carbamate (CAS: 22785-43-9) safe?

Benzyl [(3S)-2,6-dioxo-3-piperidinyl]carbamate is generally safe when handled wi...

22785-43-9Benzyl [(3S)-2,6-dio...
Compound Q&A

How should 1-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonyl}pyrrolidine (CAS: 928657-21-0) be stored?

1-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonyl}pyrrolidine s...

928657-21-01-{[4-(4,4,5,5-Tetra...

Source Journal

New Journal of Chemistry

New Journal of Chemistry
CiteScore: 5.3
Self-citation Rate: 3.7%
Articles per Year: 2153

NJC (New Journal of Chemistry) is a broad-based primary journal encompassing all branches of chemistry and its sub-disciplines. It contains full research articles, communications, perspectives and focus articles. This well-established journal, owned by the Centre National de la Recherche Scientifique (CNRS) of France, has been co-published with the Royal Society of Chemistry since January 1998. NJC is the forum for the publication of high-quality, original and significant work that opens new directions in chemistry or other scientific disciplines. In addition to having a significant chemical component, work published in NJC must demonstrate that it will have an impact on areas of research other than that of the reported work.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.