A Ru-catalyzed desulfonylative C-arylation of O-tosyl-hydroxamates

Literature Information

Publication Date 2023-12-19
DOI 10.1039/D3CC05825E
Impact Factor 6.222
Authors

Guobao Li, Tilo Lübken, Bernd Plietker


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Abstract

Benzylic amine derivatives are ubiquitous structural motifs in organic chemistry. Herein we report a direct synthesis of these compounds via a direct desulfonylative C-arylation of O-tosyl hydroxamates. The applicability of this Ru-catalyzed aminoalkylation is being exemplified by a set of late-stage functionalizations of natural products.

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