Potassium xanthate-promoted reductive sulfuration reaction: from aldehydes to thiol, disulfide, and thioester derivatives
Literature Information
Yingqi Feng, Jinli Nie, Sijie Xie, Ziqing He, Huanliang Hong, Jian Li, Yubing Huang, Lu Chen, Yibiao Li
Herein, we developed a synthetic strategy for the direct construction of C–S bonds to obtain biologically active sulfur-containing compounds and a methodology involving the reductive sulfuration of aldehydes or ketones to obtain diverse substituted thiol, disulfide, and thioester derivatives. EtOCS2K is demonstrated as a potential substitute for the Berzelius reagent or Lawesson's reagent for the construction of C–S bonds.
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