Potassium xanthate-promoted reductive sulfuration reaction: from aldehydes to thiol, disulfide, and thioester derivatives

Literature Information

Publication Date 2023-12-26
DOI 10.1039/D3CC05637F
Impact Factor 6.222
Authors

Yingqi Feng, Jinli Nie, Sijie Xie, Ziqing He, Huanliang Hong, Jian Li, Yubing Huang, Lu Chen, Yibiao Li


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Abstract

Herein, we developed a synthetic strategy for the direct construction of C–S bonds to obtain biologically active sulfur-containing compounds and a methodology involving the reductive sulfuration of aldehydes or ketones to obtain diverse substituted thiol, disulfide, and thioester derivatives. EtOCS2K is demonstrated as a potential substitute for the Berzelius reagent or Lawesson's reagent for the construction of C–S bonds.

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