Electrochemical decarboxylative alkylation of β-ketoacids with phenol derivatives
Literature Information
Shan Wang, Zhaotian Wu, Junqiang Li, Yujun Zhu, Shaojun Zheng, Chunhui Jiang, Hongfei Lu
An electrochemical method for the decarboxylative alkylation of β-ketoacids with phenol derivatives has been developed. The protocol was carried out in readily available unseparated cells at room temperature in the absence of catalysts and oxidants. The corresponding aryl ketones were obtained in satisfactory yields without additional electrolytes, and were easy to produce in gram-scale synthesis. Based on control experiments and cyclic voltammetry, a plausible reaction mechanism was proposed.
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