Electrochemical decarboxylative alkylation of β-ketoacids with phenol derivatives

Literature Information

Publication Date 2024-01-02
DOI 10.1039/D3CC05489F
Impact Factor 6.222
Authors

Shan Wang, Zhaotian Wu, Junqiang Li, Yujun Zhu, Shaojun Zheng, Chunhui Jiang, Hongfei Lu


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Abstract

An electrochemical method for the decarboxylative alkylation of β-ketoacids with phenol derivatives has been developed. The protocol was carried out in readily available unseparated cells at room temperature in the absence of catalysts and oxidants. The corresponding aryl ketones were obtained in satisfactory yields without additional electrolytes, and were easy to produce in gram-scale synthesis. Based on control experiments and cyclic voltammetry, a plausible reaction mechanism was proposed.

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Chemical Communications
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