Bioinspired cyclization of in situ generated γ-indolyl β,γ-unsaturated α-keto esters via an oxidative enamine process: facile approaches to pyrano[2,3-b]indoles
Literature Information
Publication Date
2021-09-17
DOI
10.1039/D1QO00996F
Impact Factor
5.281
Authors
Man Wang, Qirui Xiang, Wen Si, Ran Song, Daoshan Yang, Ming Li, Jian Lv
View Original
Abstract
A bioinspired cyclization of in situ generated γ-indolyl β,γ-unsaturated α-ketoesters with an oxoammonium salt via an oxidative enamine process has been developed. Under mild conditions, the reactions afforded pyrano[2,3-b]indoles, which are found in a wide range of bioactive compounds, in good yields (up to 86% yield).
Related Literature
Thermoreversible sol–gel transition of an aqueous solution of polyrotaxane composed of highly methylated α-cyclodextrin and polyethylene glycol
Masatoshi Kidowaki, Toshiyuki Kataoka
2006-08-21
Communication
DOI: 10.1039/B607373E
A low molecular weight hydrogel which exhibits electroosmotic flow and its use as a bioreactor and for electrochromatography of neutral species
Shaul Mizrahi, Dan Rizkov, Netanel Hayat, Ovadia Lev
2008-04-14
Communication
DOI: 10.1039/B802155D
Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds
Elizabeth Anne Hillard, Fabiane Caxico de Abreu, Danielle Cristhina Melo Ferreira, Gérard Jaouen, Marília Oliveira Fonseca Goulart, Christian Amatore
2008-04-10
Feature Article
DOI: 10.1039/B718116G
Formal total synthesis of (−)-haouamine A‡
Alois Fürstner, Jens Ackerstaff
2008-06-02
Communication
DOI: 10.1039/B805295F
Ruthenium–indenylidene complexes: powerful tools for metathesis transformations
Fabien Boeda, Hervé Clavier, Steven P. Nolan
2008-05-20
Feature Article
DOI: 10.1039/B718287B
Microwave-assisted catalytic allylation of aldehydes promoted by a mesoporous silica-supported BINOL ligand in solid media
Guohua Liu, Yan Gao, Xiaoquan Lu, Mouming Liu, Fang Zhang, Hexing Li
2008-04-29
Communication
DOI: 10.1039/B803111H
Solvents for ring-closing metathesis reactions
Claire S. Adjiman, Adam J. Clarke, Gregory Cooper, Paul C. Taylor
2008-04-28
Communication
DOI: 10.1039/B802921K
Cathodic chemistry of high performance Zr coated alkaline materials
Stuart Licht, Xingwen Yu, Dong Zheng
2006-09-05
Communication
DOI: 10.1039/B608716G
Detection of zinc ions under aqueous conditions using chirality assisted solid-state fluorescence of a bipyridyl based fluorophore
Sivaramapanicker Sreejith, Kizhumuri P. Divya, Ayyappanpillai Ajayaghosh
2008-04-23
Communication
DOI: 10.1039/B802958J
You might also like
Compound Q&A
What are the main uses of 4-Nitrophenyl phosphate disodium salt hexahydrate (CAS: 333338-18-4)?
4-Nitrophenyl phosphate disodium salt hexahydrate is primarily used as a substra...
333338-18-44-Nitrophenyl phosph...
Compound Q&A
What are the main uses of 2-(Trifluoromethyl)-1,3-oxazole-4-carboxylic Acid (CAS: 1060816-01-4)?
2-(Trifluoromethyl)-1,3-oxazole-4-carboxylic Acid (CAS: 1060816-01-4) is widely ...
1060816-01-42-(Trifluoromethyl)-...
Compound Q&A
How should 2-Fluoro-4-biphenylcarboxylic acid (CAS: 137045-30-8) be stored?
2-Fluoro-4-biphenylcarboxylic acid should be stored in a cool, dry place at room...
137045-30-82-Fluoro-4-biphenylc...
Compound Q&A
What industries use Prednisolone-21-Carboxylic Acid (CAS: 61549-70-0)?
Prednisolone-21-Carboxylic Acid is primarily used in the pharmaceutical industry...
61549-70-0Prednisolone-21-Carb...
Compound Q&A
How should 4-(Hydrazinomethyl)-1,2,3-benzenetriol (CAS: 3614-72-0) be stored?
4-(Hydrazinomethyl)-1,2,3-benzenetriol (CAS: 3614-72-0) should be stored in a co...
3614-72-04-(Hydrazinomethyl)-...
Compound Q&A
What industries use 4-Amino-1-methyl-1H-pyrazole-5-carboxylic acid hydrochloride (CAS: 92534-70-8)?
4-Amino-1-methyl-1H-pyrazole-5-carboxylic acid hydrochloride (CAS: 92534-70-8) i...
92534-70-84-Amino-1-methyl-1H-...
Compound Q&A
What regulatory guidelines apply to dehydropachymic acid (CAS: 77012-31-8)?
Dehydropachymic acid (CAS: 77012-31-8) is regulated by various agencies. It fall...
77012-31-8Dehydropachymic acid
Compound Q&A
What is the market or research trend for 6-[(2,2-Dimethylpropanoyl)amino]nicotinic acid (CAS: 898561-66-5)?
The market and research trends for 6-[(2,2-Dimethylpropanoyl)amino]nicotinic aci...
898561-66-56-[(2,2-Dimethylprop...
Compound Q&A
How should 1,10-Phenanthroline-2,9-dicarbaldehyde (CAS: 57709-62-3) be stored?
1,10-Phenanthroline-2,9-dicarbaldehyde should be stored in a cool, dry place awa...
57709-62-31,10-Phenanthroline-...
Compound Q&A
How is 5-Carbamoyl-11-oxo-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate (CAS: 113952-21-9) typically synthesized?
5-Carbamoyl-11-oxo-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate can be synt...
113952-21-95-Carbamoyl-11-oxo-1...
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.