Aqueous ROPISA of α-amino acid N-carboxyanhydrides: polypeptide block secondary structure controls nanoparticle shape anisotropy
Literature Information
Publication Date
2021-09-21
DOI
10.1039/D1PY00995H
Impact Factor
5.582
Authors
Pedro Salas-Ambrosio, Ségolène Antoine, Emmanuel Ibarboure, Olivier Sandre, Mark W. Grinstaff, Sébastien Lecommandoux, Colin Bonduelle
View Original
Abstract
Polymerization-induced self-assembly (PISA) is an efficient one-step process to obtain nanomaterials. In this work, aqueous ring-opening polymerization induced self-assembly (ROPISA) of α-amino acid N-carboxyanhydride (NCA) affords controllable well-defined nanoassemblies. ROPISA with the PEG5 kDa-NH2 macroinitiator and either the benzyl-L-glutamate NCA (BLGNCA) or L-leucine NCA (LeuNCA) monomer yields amphiphilic block copolymers, with different polypeptide molar masses, which spontaneously form nanostructures. In contrast to the previous PISA process where the hydrophobic to hydrophilic ratio was the main parameter defining nanomaterial morphology, the secondary structure of the polypeptides is the main driving force to stabilize the anisotropic rod-like nanostructures with this ROPISA process.
Related Literature
Detection of chemical warfare agent simulants and hydrolysis products in biological samples by paper spray mass spectrometry
Josiah McKenna, Elizabeth S. Dhummakupt, Theresa Connell, Paul S. Demond, Dennis B. Miller, J. Michael Nilles, Nicholas E. Manicke, Trevor Glaros
2017-03-17
Paper
DOI: 10.1039/C7AN00144D
Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)
Sang-Yong Lee, Xihuan Luo, Vigneshwaran Namasivayam, Jennifer Geiss, Salahuddin Mirza, Julie Pelletier, Holger Stephan, Christa E. Müller
2018-10-02
Paper
DOI: 10.1039/C8AN01108G
Raman spectroscopy and multivariate analysis for the non invasive diagnosis of clinically inconclusive vulval lichen sclerosus
Linmarie Ludeman, Kathryn Hillaby, Robert Gornall, Gavin Lloyd, Catherine Kendall, Angela C. Shore, Nick Stone
2016-11-03
Paper
DOI: 10.1039/C6AN02009G
Design of a simple paper-based colorimetric biosensor using polydiacetylene liposomes for neomycin detection
Do Hyun Kang, Keesung Kim, Younghwan Son, Pahn-Shick Chang, Ho-Sup Jung
2018-09-04
Paper
DOI: 10.1039/C8AN01097H
A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering
Chen Zeng, Fanghao Hu, Rong Long, Wei Min
2018-09-03
Communication
DOI: 10.1039/C8AN00910D
Two new quinoline-based regenerable fluorescent probes with AIE characteristics for selective recognition of Cu2+ in aqueous solution and test strips
Jingwen Xiong, Zongzhi Li, Jihua Tan, Shaomin Ji, Jianwei Sun, Xianwei Li, Yanping Huo
2018-08-01
Paper
DOI: 10.1039/C8AN00940F
Multi-lumen capillary based trypsin micro-reactor for the rapid digestion of proteins
S. A. Currivan, W. Q. Chen, R. Wilson, E. Sanz Rodriguez, N. Upadhyay, D. Connolly
2018-09-10
Paper
DOI: 10.1039/C8AN01330F
Efficient synthesis of riboflavin-imprinted magnetic nanoparticles by boronate affinity-based surface imprinting for the selective recognition of riboflavin
Daojin Li, Zijun Bie, Fangfang Wang, Enhui Guo
2018-09-06
Paper
DOI: 10.1039/C8AN01044G
You might also like
Compound Q&A
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
52818-63-0N-(4-Methoxybenzyl)-...
Compound Q&A
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
1050507-06-6Ethyl 4-(2-chlorophe...
Compound Q&A
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
628-39-7Diethyldiselane
Compound Q&A
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
12053-18-8oxocopper; oxo-(oxoc...
Compound Q&A
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
1268519-54-55-{[(2-Methyl-2-prop...
Compound Q&A
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
35981-63-62-(1-Pyrrolidinyl)-4...
Compound Q&A
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
91556-75-12-(3-Pyridinyl)-1-az...
Compound Q&A
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
129704-91-2(S)-Alpha-allyl-prol...
Compound Q&A
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
4857-42-53-Methyl-1,2-oxazole...
Compound Q&A
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
1281816-04-3Lys-SMCC-DM1
Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
Benzyl 6-oxo-3,6-dihydro-1(2H)-pyridinecarboxylate
CAS Number:
725746-35-0
Molecular Formula:
C13H13NO3
![5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure](https://static.chemtradehub.com/structs/251/251903-00-1-9cb1.webp "5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure")
(2R)-2-(3-Bromophenyl)pyrrolidine hydrochloride (1:1)
CAS Number:
1391550-13-2
Molecular Formula:
C10H13BrClN
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.