Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

Literature Information

Publication Date 2021-01-15
DOI 10.1039/D0MD00347F
Impact Factor 0
Authors

Baris A. Borsa, Mert Sudagidan, Mehmet E. Aldag, Isik I. Baris, Elif E. Acar, Cagatay Acuner, Murat Kavruk, Veli C. Ozalp


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Abstract

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for S. aureus infection.

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