Copper-catalysed oxidative α-C(sp3)–H nitroalkylation of (hetero)arene-fused cyclic amines
Literature Information
Publication Date
2019-12-12
DOI
10.1039/C9QO01208G
Impact Factor
5.281
Authors
Xiu Li, He Zhao, Xiuwen Chen, Huanfeng Jiang
View Original
Abstract
Under aerobic copper catalysis, we herein report a direct α-C(sp3)–H nitroalkylation of N-unsubstituted (hetero)arene-fused cyclic amines with nitroalkanes. The transformation proceeds with good substrate and functional group compatibility, high step and atom efficiency, and operational simplicity.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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2,2'-{2,2-Propanediylbis[(2,6-dibromo-4,1-phenylene)oxy]}diethanol
CAS Number:
4162-45-2
Molecular Formula:
C19H20Br4O4
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