Highly efficient enantioselective synthesis of bispiro[benzofuran-oxindole-pyrrolidine]s through organocatalytic cycloaddition
Literature Information
Boyu Li, Fengyun Gao, Xing Feng, Mengmeng Sun, Yifei Guo, Dongwa Wen, Yabo Deng, Jinqi Huang, Kairong Wang, Wenjin Yan
A series of compounds featuring novel bispiro[benzofuran-oxindole-pyrrolidine] moieties have been achieved through a thiourea-catalyzed 1,3-dipolar cycloaddition reaction. The Michael/Mannich reaction of N-2,2,2-trifluoroethylisatin ketimines with aurones furnished the cycloadducts in excellent yields with excellent stereoselectivities.
Related Literature
Adding water to sugar: A spectroscopic and computational study of α- and β-phenylxyloside in the gas phase
Isabel Hünig, Alexander J. Painter, Rebecca A. Jockusch, Pierre Çarçabal, Elaine M. Marzluff, Lavina C. Snoek, David P. Gamblin, Benjamin G. Davis, John P. Simons
DOI: 10.1039/B504230E
Vibrational analysis of capped [Leu]enkephalin
Tim M. Watson, Jonathan D. Hirst
DOI: 10.1039/B315501C
Reactions of platinum clusters 195Ptn±, n = 1–24, with N2O studied with isotopically enriched platinum
Iulia Balteanu, O. Petru Balaj, Martin K. Beyer, Vladimir E. Bondybey
DOI: 10.1039/B405211K
Characterisation of the water/o-nitrophenyl octyl ether system in terms of the partition of nonelectrolytes and of ions
Michael H. Abraham, Yuan H. Zhao
DOI: 10.1039/B502058A
Linear relationship between activation energies and reaction energies for coverage-dependent dissociation reactions on rhodium surfaces
Oliver R. Inderwildi, Dirk Lebiedz, Jürgen Warnatz
DOI: 10.1039/B506773A
Molecular dynamics simulation of the squarate anion in acetonitrile solution
Ary O. Cavalcante, Sérgio M. Urahata, Mauro C. C. Ribeiro
DOI: 10.1039/B402413C
Thermal and physical properties of an archetypal organic ionic plastic crystal electrolyte
Steven J. Pas, Jennifer M. Pringle, Maria Forsyth, Douglas R. MacFarlane
DOI: 10.1039/B400452C
Interactions of hydrated divalent metal cations with nucleic acid bases. How to relate the gas phase data to solution situation and binding selectivity in nucleic acids
Judit E. Šponer, Vladimír Sychrovský, Pavel Hobza
DOI: 10.1039/B404306P
Electrochemical control of glucose oxidase-catalyzed redox reaction using an oil/water interface
Takayasu Sugihara, Hiroki Hotta, Toshiyuki Osakai
DOI: 10.1039/B400338A
You might also like
How should waste containing (6-Bromo-2-naphthyl)oxy](dimethyl)(2-methyl-2-propanyl)silane be handled?
Waste containing (6-Bromo-2-naphthyl)oxy](dimethyl)(2-methyl-2-propanyl)silane (...
How is 7-Fluoro-4-isoquinolinecarboxylic acid (CAS: 1841081-40-0) typically synthesized?
7-Fluoro-4-isoquinolinecarboxylic acid can be synthesized via a multi-step proce...
What are the physical and chemical properties of 2,3,5,6-Tetrabromothieno[3,2-b]thiophene (CAS: 124638-53-5)?
2,3,5,6-Tetrabromothieno[3,2-b]thiophene is a crystalline compound with a high m...
Is 1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide (CAS: 1542705-92-9) safe?
1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indol...
What is the market or research trend for imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo- (CAS: 113942-30-6)?
The market for imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3...
What is 3-(Triisopropylsilyl)propiolaldehyde (CAS: 163271-80-5)?
3-(Triisopropylsilyl)propiolaldehyde is a synthetic organic compound with the CA...
What regulatory guidelines apply to 6-Nitro-2H-1,4-benzoxazin-3(4H)-one (CAS: 81721-87-1)?
6-Nitro-2H-1,4-benzoxazin-3(4H)-one (CAS: 81721-87-1) is subject to various regu...
How should waste containing (3-Fluorophenyl)(4-{[(2-methyl-2-propanyl)oxy]carbonyl}-1-piperazinyl)acetic acid (CAS: 885272-91-3) be handled?
Waste containing (3-Fluorophenyl)(4-{[(2-methyl-2-propanyl)oxy]carbonyl}-1-piper...
What are the physical and chemical properties of N,N'-4,4'-Biphenyldiyldiisonicotinamide (CAS: 55119-40-9)?
N,N'-4,4'-Biphenyldiyldiisonicotinamide is a white crystalline solid with a mole...
What industries use 6-Bromo-8-fluoro-2-quinazolinol (CAS: 1036756-15-6)?
6-Bromo-8-fluoro-2-quinazolinol is primarily used in the pharmaceutical industry...
Source Journal
Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry










![N-[(E)-Phenylmethylene]benzenesulfonamide structure N-[(E)-Phenylmethylene]benzenesulfonamide structure](https://static.chemtradehub.com/structs/139/13909-34-7-8167.webp)


![2,9-Dichloro-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione structure 2,9-Dichloro-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione structure](https://static.chemtradehub.com/structs/308/3089-17-6-750b.webp)
