Palladium-catalyzed diastereo- and enantioselective formal [3 + 2] cycloaddition of vinyl cyclopropanes with cyclic 1-azadienes

Literature Information

Publication Date 2019-04-15
DOI 10.1039/C9QO00325H
Impact Factor 5.281
Authors

Qing Zhou, Bo Chen, Xiao-Bing Huang, Ya-Li Zeng, Wen-Dao Chu, Quan-Zhong Liu


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Abstract

Palladium-catalyzed asymmetric formal [3 + 2] cycloadditions of vinyl cyclopropanes and cyclic 1-azadienes proceeded smoothly in the presence of chiral phosphoramidite ligands to afford the corresponding highly functionalized cyclopentanes in good yields along with high enantioselectivities under mild conditions.

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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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