Silver-catalyzed cascade radical cyclization of 2-(allyloxy)arylaldehydes with cyclopropanols: access to chroman-4-one derivatives

Literature Information

Publication Date 2019-03-18
DOI 10.1039/C9QO00292H
Impact Factor 5.281
Authors

Jie Sheng, Liuqing Chen, Lingling Zhang, Liyao Zheng, Xingchuan Wei


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Abstract

A novel silver-catalyzed cascade radical cyclization of 2-(allyloxy)arylaldehydes with cyclopropanols was developed to synthesize carbonyl-containing alkyl-substituted chroman-4-one derivatives. This transformation is easy to conduct under mild oxidative conditions to generate two carbon–carbon bonds in a cascade radical sequence with a broad substrate scope.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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