In situ synthesis of protein-loaded hydrogels via biocatalytic ATRP

Literature Information

Publication Date 2020-01-08
DOI 10.1039/C9PY01815H
Impact Factor 5.582
Authors


View Original

Abstract

Protein-loaded hydrogels were synthesized via biocatalytic atom transfer radical polymerization (ATRP) for the first time. Laccase from Trametes versicolor acted as the ATRPase for the enzymatic polymerizations and was in situ loaded into the porous network of poly(ethylene glycol)-based hydrogels. The use of additional ligands such as tris(2-(dimethylamino)ethyl)amine could significantly increase the polymerization conversion, allowing the polymerizations to occur at ambient or even lower temperature. The rheology and water uptake ratio of hydrogels could be tuned by using different cross-linkers. Immobilized enzymes in the hydrogels have shown decreased yet considerable activity compared with pristine laccase. The hydrogels could be facilely recovered and reused up to six times with no significant decrease in enzyme activity. Such hydrogels were successfully used for the oxidative polymerization of hydroquinone and may find potential applications in protein delivery and water treatment.

Related Literature

The reactions of cytidine and 2′-deoxycytidine with SO4˙− revisited. Pulse radiolysis and product studies

Charuvila T. Aravindakumar, Man Nien Schuchmann, Balijepalli S. M. Rao, Justus von Sonntag

2002-12-09 Paper

DOI: 10.1039/B209626A

The type I rat fatty acid synthase ACP shows structural homology and analogous biochemical properties to type II ACPs

Michelle A. C. Reed, Michael Schweizer, Anna E. Szafranska, Chris Arthur, Thomas P. Nicholson, Russell J. Cox, John Crosby, Matthew P. Crump, Thomas J. Simpson

2003-01-03 Paper

DOI: 10.1039/B208941F

A donor–acceptor substituted molecular motor: unidirectional rotation driven by visible light

Richard A. van Delden, Nagatoshi Koumura, Annemarie Schoevaars, Auke Meetsma, Ben L. Feringa

2002-11-08 Communication

DOI: 10.1039/B209378B

Synthesis of stereochemically-biased spiropyrans by microwave-promoted, one-pot alkylation–condensation

Alexis Perry, Kane Davis, Lara West

2018-09-21 Paper

DOI: 10.1039/C8OB01996G

Intramolecular charge transfer with N-benzoylaminonaphthalenes. 1-Aminonaphthaleneversus2-aminonaphthalene as electron donors

Xuan Zhang, Chun-Hua Liu, Li-Hong Liu, Lin Guo, Chao-Jie Wang, Yun-Bao Jiang

2003-01-29 Paper

DOI: 10.1039/B210106H

Resolution of the non-steady-state kinetics of the elimination of HBr from 2-(p-nitrophenyl)ethyl bromide in alcohol/alkoxide media

Kishan L. Handoo, Yun Lu, Yixing Zhao, Vernon D. Parker

2002-11-21 Communication

DOI: 10.1039/B208634D

First synthesis of 2′,3′-epimino-carbocyclic nucleosides

Minoru Ishikura, Atsushi Murakami, Nobuya Katagiri

2003-01-07 Communication

DOI: 10.1039/B210963H

Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity

Christian Lerner, Birgit Masjost, Armin Ruf, Volker Gramlich, Roland Jakob-Roetne, Gerhard Zürcher, Edilio Borroni, François Diederich

2002-11-26 Paper

DOI: 10.1039/B208690P

Dirhodium(ii)-catalyzed ortho C–H amination of sterically congested N,N-dialkylanilines

Motoki Ito, Tomoya Nakagawa, Kazuhiro Higuchi, Shigeo Sugiyama

2018-09-12 Communication

DOI: 10.1039/C8OB01974F

Experimental charge density of octafluoro-1,2-dimethylenecyclobutane: atomic volumes and charges in a perfluorinated hydrocarbon

Dieter Lentz, Mona Patzschke, Ansgar Bach, Stephan Scheins, Peter Luger

2002-12-17 Paper

DOI: 10.1039/B208704A

You might also like

Compound Q&A

Is 4-Benzyl-2,2-dimethylmorpholine (CAS: 84761-04-6) safe?

4-Benzyl-2,2-dimethylmorpholine is generally considered safe when handled under ...

84761-04-64-Benzyl-2,2-dimethy...
Compound Q&A

What is (5,6-Dimethoxy-3-pyridinyl)boronic acid (CAS: 1346526-61-1)?

(5,6-Dimethoxy-3-pyridinyl)boronic acid is a chemical compound with the molecula...

1346526-61-1(5,6-Dimethoxy-3-pyr...
Compound Q&A

How is 1,1,3,3-Tetramethyl-1,3-bis(2-methyl-2-propanyl)disiloxane (CAS: 67875-55-2) typically synthesized?

1,1,3,3-Tetramethyl-1,3-bis(2-methyl-2-propanyl)disiloxane is synthesized throug...

67875-55-21,1,3,3-Tetramethyl-...
Compound Q&A

What are the main uses of (2R,4S)-1-Boc-4-methylpyrrolidine-2-carboxylic acid (CAS: 1018818-04-6)?

(2R,4S)-1-Boc-4-methylpyrrolidine-2-carboxylic acid is primarily used as a build...

1018818-04-6(2R,4S)-1-Boc-4-meth...
Compound Q&A

What precautions should be taken when handling 2,3-Dichloroacrylonitrile (CAS: 22410-58-8)?

When handling 2,3-Dichloroacrylonitrile, it is crucial to wear appropriate perso...

22410-58-82,3-Dichloroacryloni...
Compound Q&A

How should (S)-1-(o-Tolyl)ethanamine hydrochloride (CAS: 1332832-16-2) be stored?

(S)-1-(o-Tolyl)ethanamine hydrochloride should be stored in a cool, dry place to...

1332832-16-2(S)-1-(o-Tolyl)ethan...
Compound Q&A

What are the physical and chemical properties of Benzyl [1-(hydroxyamino)-1-imino-2-methyl-2-propanyl]carbamate (CAS: 518047-98-8)?

Benzyl [1-(hydroxyamino)-1-imino-2-methyl-2-propanyl]carbamate (CAS: 518047-98-8...

518047-98-8Benzyl [1-(hydroxyam...
Compound Q&A

What industries use 2-Methyloxazole-5-carbaldehyde (CAS: 885273-42-7)?

2-Methyloxazole-5-carbaldehyde is used in the pharmaceutical industry for the sy...

885273-42-72-Methyloxazole-5-ca...
Compound Q&A

What is the market or research trend for 2-Methyl-2-propanyl 4-[(1S)-1-hydroxyethyl]-1-piperidinecarboxylate (CAS: 389889-82-1)?

The market for 2-Methyl-2-propanyl 4-[(1S)-1-hydroxyethyl]-1-piperidinecarboxyla...

389889-82-12-Methyl-2-propanyl ...
Compound Q&A

Is 1-Butyl-3-methylpyridinium bromide (CAS: 26576-85-2) safe?

1-Butyl-3-methylpyridinium bromide is generally considered safe for laboratory u...

26576-85-21-Butyl-3-methylpyri...

Source Journal

Polymer Chemistry

Polymer Chemistry
CiteScore: 8.6
Self-citation Rate: 7.3%
Articles per Year: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.