CuBr2-catalyzed diastereoselective allylation: total synthesis of decytospolides A and B and their C6-epimers
Literature Information
Birakishore Padhi, G. Sudhakar Reddy, N. Arjunreddy Mallampudi, Utkal Mani Choudhury, Debendra K. Mohapatra
An efficient CuBr2-catalyzed diastereoselective allylation of a cyclic hemiacetal with allyltrimethylsilane as a nucleophile has been developed. The protocol offers a cost effective, protecting group tolerant, and operationally simple approach to 2,6-trans-disubstituted tetrahydropyran with excellent diastereoselectivity. Furthermore, the application of this methodology has been demonstrated in the total synthesis of decytospolides A and B and their C6-epimers.
Recommended Journals

Drug Discovery Today

Current Opinion in Colloid & Interface Science

Chemical Communications

Russian Journal of Bioorganic Chemistry

Journal of Natural Medicines

Current Opinion in Solid State & Materials Science

Journal of Peptide Science

Russian Journal of Organic Chemistry

Russian Journal of Applied Chemistry

Crystallography Reports
Related Literature
Nanoscale Horizons Emerging Investigator Series: Dr Ahu Gümrah Dumanli-Parry, University of Manchester, UK
DOI: 10.1039/D3NH90048G
Contact engineering for 2D Janus MoSSe/metal junctions
Yu Shu, Ting Li, Naihua Miao, Jian Gou, Xiaochun Huang, Zhou Cui, Rui Xiong, Cuilian Wen, Jian Zhou, Baisheng Sa, Zhimei Sun
DOI: 10.1039/D3NH00450C
Strategy for enhancement of magnesium ion diffusion in a vanadium tetra sulfide-layered structure for rechargeable magnesium batteries
Muhammad Kashif Naseem, Mian Azmat, Changliang Du, Rong Jiang, Hajra, Youqi Zhu, Meishuai Zou, Chuanbao Cao
DOI: 10.1039/D3TA04634F
In situ formation of a ZnS/In interphase for reversible Zn metal anodes at ultrahigh currents and capacities
Chengwu Yang, Pattaraporn Woottapanit, Jin Cao, Yilei Yue, Dongdong Zhang, Jin Yi, Zhiyuan Zeng, Xinyu Zhang, Jiaqian Qin, Yonggang Wang
DOI: 10.1039/D3TA05650C
Crystal structure, infrared spectroscopy and thermodynamic properties of a manganese member of the ellenbergerite family
Larisa V. Shvanskaya, Polina V. Krikunova, Tatyana M. Vasilchikova, Elena Y. Borovikova, Olga S. Volkova, Alexander N. Vasiliev
DOI: 10.1039/D3NJ05142K
SiO2 supported Ce–Co mixed oxide catalyzed selective allylic oxidation of cyclohexene
Aratikumari Suresh Prasad
DOI: 10.1039/D3NJ04852G
Solar light selective-harvesting eco-friendly colloidal quantum dots for transparent luminescent solar concentrators
Ehsan Hamzehpoor, Jiabin Liu, Xin Liu, Gurpreet Singh Selopal, Dmytro F. Perepichka, Zhiming M. Wang
DOI: 10.1039/D3TA05351B
Ultrahigh-quality graphene resonators by liquid-based strain-engineering
Mario Hofmann, Chi-Te Liang, Ya-Ping Hsieh
DOI: 10.1039/D3NH00420A
You might also like
What regulatory guidelines apply to 6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1)?
6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1) falls under various...
Are there alternatives to 1-Pyrrolidineethanol, β-methyl-α-phenyl-, (αS,βR) (CAS: 123620-80-4) in synthesis?
While there are no direct alternatives, similar compounds like 1-Pyrrolidineetha...
Is 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) safe?
4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) is ...
How should 2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) be stored?
2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) should be stored in a...
What are the physical and chemical properties of 4,5,6,7-Tetrahydro-1H-indazole hydrochloride (CAS: 18161-11-0)?
4,5,6,7-Tetrahydro-1H-indazole hydrochloride is a white crystalline solid with a...
What is (2R)-1-Methoxy-3-phenyl-2-propanamine (CAS: 59919-07-2)?
(2R)-1-Methoxy-3-phenyl-2-propanamine is a chiral organic compound with the CAS ...
What industries use Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate (CAS: 56649-47-9)?
Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate is used in various industries...
What regulatory guidelines apply to 4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3)?
4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3) falls...
What industries use (S)-3-Amino-5-phenylpentanoic acid hydrochloride (CAS: 331846-97-0)?
(S)-3-Amino-5-phenylpentanoic acid hydrochloride is primarily used in the pharma...
How is 7-methoxy-1-benzothiophene-2-carboxylic acid (CAS: 88791-07-5) typically synthesized?
7-Methoxy-1-benzothiophene-2-carboxylic acid is typically synthesized by reactin...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.




