Base-free, tunable, Au-catalyzed oxidative esterification of alcohols in continuous flow
Literature Information
Felicity J. Roberts, Christian Richard, Fessehaye W. Zemichael, King Kuok (Mimi) Hii, Klaus Hellgardt, Colin Brennan, David A. Sale
Under continuous flow conditions, hydrogen peroxide oxidizes primary alcohols (cinnamyl alcohol, decenol, decanol and benzyl alcohol) in methanol over Au/TiO2, without the need for added base. While the allylic alcohols afforded conjugated aldehydes, aliphatic and benzylic alcohols afforded acids or esters. Selectivity for either product can be achieved by adjusting the reaction parameters. Kinetic studies revealed that the formation of the easter is faster than that of the acid, due to a greater pre-organization (larger ln A) attributed to the more favourable formation of the hemiacetal intermediate.
Related Literature
Encapsulated molecular catalysts in polysiloxane gels: ruthenium cluster-catalyzed isomerization of alkenes
Motonori Abe, Kazuyuki Kamo, Yusuke Kosako
DOI: 10.1039/B809937E
Snowman-like silver alkynyl cluster consolidated by templating chloride and peripheral trifluoroacetates
Shu-Dan Bian, Quan-Ming Wang
DOI: 10.1039/B812451E
New functional materials for heavy metal sorption: “Supramolecular” attachment of thiols to mesoporous silica substrates
Timothy G. Carter, Wassana Yantasee, Thanapon Sangvanich, Glen E. Fryxell, Darren W. Johnson, R. Shane Addleman
DOI: 10.1039/B810576F
Enantioselective synthesis of cyclopropylcarboxamides using s-BuLi–sparteine-mediated metallation
Stephanie Lauru, Nigel S. Simpkins, David Gethin, Claire Wilson
DOI: 10.1039/B810441G
An enzymatic kinetics investigation into the significantly enhanced activity of functionalized gold nanoparticles
Chung-Shu Wu, Chia-Tien Wu, Yuh-Shyong Yang, Fu-Hsiang Ko
DOI: 10.1039/B810889G
Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions
Manfred T. Reetz, Sheng Wu
DOI: 10.1039/B813388C
Heterocirculenes as a new class of organic semiconductors
Fabio Cicoira, Konstantin Yu. Chernichenko, Elizabeth S. Balenkova, Federico Rosei, Valentine G. Nenajdenko, Dmitrii F. Perepichka
DOI: 10.1039/B809259A
Water electrolysis: an excellent approach for the removal of water from ionic liquids
Md. Mominul Islam, Takeyoshi Okajima, Shimpei Kojima, Takeo Ohsaka
DOI: 10.1039/B811174J
A non-oxide sol–gel route to synthesise silicon imidonitride monolithic gels and high surface area aerogels
Shereen Hassan, Andrew L. Hector, Jason R. Hyde, Ali Kalaji, David C. Smith
DOI: 10.1039/B810317H
Facile synthesis of aminophenylboronic acid-functionalized magnetic nanoparticles for selective separation of glycopeptides and glycoproteins
Wei Zhou, Ning Yao, Guoping Yao, Chunhui Deng, Xiangmin Zhang, Pengyuan Yang
DOI: 10.1039/B808800D
You might also like
What are the main uses of 1H-Indazole-6-carbonitrile (CAS: 141290-59-7)?
1H-Indazole-6-carbonitrile finds applications in pharmaceuticals, where it serve...
How should waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) be handled?
Waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) should be collecte...
What industries use Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide (CAS: 68291-98-5)?
Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide is primarily used in pharmac...
Are there alternatives to Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxylate (CAS: 741709-66-0) in synthesis?
Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxyla...
How should waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) be handled?
Waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) should be manage...
What is 6-Formyl-2-pyridinecarboxylic acid (CAS: 499214-11-8)?
6-Formyl-2-pyridinecarboxylic acid is an organic compound with the molecular for...
What is the market or research trend for 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholin-4-ylethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS: 900874-91-1)?
Research trends for this compound indicate a focus on its potential applications...
How is 9H-Tribenzo[b,d,f]azepine (CAS: 29875-73-8) typically synthesized?
9H-Tribenzo[b,d,f]azepine is typically synthesized via a multi-step process invo...
How is 1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 1797982-51-4) typically synthesized?
1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxyli...
How should waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: 671820-52-3) be handled?
Waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: ...
Source Journal
Reaction Chemistry & Engineering

Reaction Chemistry & Engineering is an interdisciplinary journal reporting cutting-edge research focused on enhancing the understanding and efficiency of reactions. Reaction engineering leverages the interface where fundamental molecular chemistry meets chemical engineering and technology. Challenges in chemistry can be overcome by the application of new technologies, while engineers may find improved solutions for process development from the latest developments in reaction chemistry. Reaction Chemistry & Engineering is a unique forum for researchers whose interests span the broad areas of chemical engineering and chemical sciences to come together in solving problems of importance to wider society. All papers should be written to be approachable by readers across the engineering and chemical sciences. Papers that consider multiple scales, from the laboratory up to and including plant scale, are particularly encouraged.










![9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate structure 9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate structure](https://static.chemtradehub.com/structs/131/1314378-14-7-4316.webp)



