Nickel-promoted C(2)–H amidation of quinoline N-oxides with N-fluorobenzenesulfonimide
Literature Information
Shuaijun Han, Xianying Gao, Qingsong Wu, Jingya Li, Dapeng Zou, Yangjie Wu
Reported herein is an unprecedented nickel-promoted C–H amidation reaction of quinoline N-oxides using N-fluorobenzenesulfonimide (NFSI) as the amination reagent. This strategy provides a convenient access to a variety of useful 1,2-dihydro-2-iminoquinolines in moderate to good yields. Notable advantages of this protocol include easy operation and mild reaction conditions.
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Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry











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