Asymmetric phase-transfer catalysed β-addition of isoxazolidin-5-ones to MBH carbonates

Literature Information

Publication Date 2018-10-12
DOI 10.1039/C8QO01057A
Impact Factor 5.281
Authors

Katharina Zielke, Andreas Eitzinger, Antonio Massa, Laura Palombi, Kirill Faust, Mario Waser


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Abstract

A novel high yielding, enantio- and diastereoselective protocol for the synthesis of α-allylated highly functionalised β-amino acid derivatives by adding isoxazolidin-5-ones to MBH carbonates under asymmetric phase-transfer catalysis has been developed.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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