Multicomponent dipolar cycloadditions: efficient synthesis of polycyclic fused pyrrolizidines via azomethine ylides
Literature Information
Srinivas Samala, Do Hyun Ryu, Choong Eui Song, Eun Jeong Yoo
An efficient multicomponent dipolar cycloaddition for the synthesis of polycyclic fused pyrrolizidines was developed using N-aromatic zwitterions, aldehydes, and amino acids. The developed reactions proceed through azomethine ylides generated in situ from the decarboxylated reactions of aldehydes and amino acids followed by the [3 + 2] cycloaddition of N-aromatic zwitterions under mild reaction conditions.
Recommended Journals
Related Literature
Pattern transitions in a compressible floating elastic sheet
Haim Diamant
DOI: 10.1039/C7CP03239K
Probing the solvation structure and dynamics in ionic liquids by time-resolved infrared spectroscopy of 4-(dimethylamino)benzonitrile
Rômulo A. Ando, Samantha E. Brown-Xu, Lisa N. Q. Nguyen, Terry L. Gustafson
DOI: 10.1039/C7CP04961G
Running out of lithium? A route to differentiate between capacity losses and active lithium losses in lithium-ion batteries
Florian Holtstiege, Andrea Wilken, Tobias Placke
DOI: 10.1039/C7CP05405J
Ionic effects on the proton transfer mechanism in aqueous solutions
Joonyoung F. Joung, Sangin Kim, Sungnam Park
DOI: 10.1039/C7CP04392A
Relativistic effects at the Cu2O2 core – a density functional theory study
Matthias Witte, Sonja Herres-Pawlis
DOI: 10.1039/C7CP04686C
Melting kinetics of superheated crystals of glucose and fructose
Tatsiana Liavitskaya, Lily Birx, Sergey Vyazovkin
DOI: 10.1039/C7CP05486F
Quercetin and its analogues: optical and acido–basic properties
David Biedermann, Kateřina Valentová, Vladimír Křen, Martin Kubala
DOI: 10.1039/C7CP03845C
Electronic excitation induced hydrogen-bond adjustment and lattice control in organic–inorganic hybrid cubic perovskites: a fixed occupation molecular dynamics study
Mo-Ran Wang, Xiang-Yang Ren, Nian-Ke Chen, Hong-Bo Sun
DOI: 10.1039/C7CP05034H
Langmuir–Blodgett films of perylene bisimide derivatives and fluorescent recognition of diamines
Congdi Shang, Li Wang, Yanqin An, Ping Chen, Xingmao Chang, Yanyu Qi, Rui Kang, Yu Fang
DOI: 10.1039/C7CP04235C
Adsorption of molecular hydrogen on coronene with a new potential energy surface
Massimiliano Bartolomei, Ricardo Pérez de Tudela, Kilian Arteaga, Tomás González-Lezana, Marta I. Hernández, José Campos-Martínez, Pablo Villarreal, Javier Hernández-Rojas, José Bretón
DOI: 10.1039/C7CP03819D
You might also like
What is 3-Fluoro-2-methylbenzylamine (CAS: 771573-36-5)?
3-Fluoro-2-methylbenzylamine is an organic compound with the CAS number 771573-3...
Is Tert-butyl 2-(oxetan-3-ylidene)acetate (CAS: 1207175-03-8) safe?
Tert-butyl 2-(oxetan-3-ylidene)acetate is considered safe for its intended uses ...
What precautions should be taken when handling 4-Acetyl-2-fluorobenzonitrile (CAS: 214760-18-6)?
Proper personal protective equipment (PPE) such as gloves, goggles, and a lab co...
How is 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6) typically synthesized?
2-Ethyl-4-methyl-1,3-thiazole is commonly synthesized via the reaction of thiour...
How should 5',5''-([2,2'-Bithiophene]-5,5'-diyl)bis(([1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid)) (CAS: 1227780-71-3) be stored?
This compound should be stored in a cool, dry place away from direct sunlight an...
What regulatory guidelines apply to L-Lysine Acetate Salt (CAS: 52315-92-1)?
L-Lysine Acetate Salt (CAS: 52315-92-1) is subject to various regulatory guideli...
Is 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) safe?
6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) is generally conside...
What are the physical and chemical properties of 1,1'-Sulfonylbis(1H-imidazole) (CAS: 7189-69-7)?
1,1'-Sulfonylbis(1H-imidazole) is a crystalline solid with a molecular weight of...
What industries use 4-methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5)?
4-Methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5) is primarily used i...
How should waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) be handled?
Waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) should be ...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.











![O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine structure O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine structure](https://static.chemtradehub.com/structs/198/198561-81-8-a56e.webp)


![(3R)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid structure (3R)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid structure](https://static.chemtradehub.com/structs/500/500789-04-8-20dd.webp)